Question: What Are The Types Of Thalassemia?

What are the 4 types of alpha thalassemia?

There are 4 types of alpha thalassemia:Alpha thalassemia silent carrier.

One gene is missing or damaged, and the other 3 are normal.

Blood tests are usually normal.

Alpha thalassemia carrier.

Two genes are missing.

Hemoglobin H disease.

Three genes are missing.

Alpha thalassemia major.

All 4 genes are missing..

What are the types of beta thalassemia?

Beta thalassemia is classified into two types depending on the severity of symptoms: thalassemia major (also known as Cooley’s anemia) and thalassemia intermedia. Of the two types, thalassemia major is more severe. The signs and symptoms of thalassemia major appear within the first 2 years of life.

What are the main causes of thalassemia?

Thalassemia is caused by mutations in the DNA of cells that make hemoglobin — the substance in red blood cells that carries oxygen throughout your body. The mutations associated with thalassemia are passed from parents to children.

Can thalassemia major marry?

Abstract. Aim: With good care, patients with transfusion-dependent thalassemia major (TDTM) can reach older ages, marry and reproduce.

Is thalassemia a serious disease?

Beta Thalassemia Major (also called Cooley’s Anemia) is a serious illness. Symptoms appear in the first two years of life and include paleness of the skin, poor appetite, irritability, and failure to grow. Proper treatment includes routine blood transfusions and other therapies.

At what age is thalassemia detected?

Most children with moderate to severe thalassemia receive a diagnosis by the time they are 2 years old. People with no symptoms may not realize that they are carriers until they have a child with thalassemia.

Can thalassemia minor get married?

If anyone is a carrier and gets married to a person with normal genotype, there is a 50% chance / possibility of having an offspring with thalassaemia carrier status. However, no thalassaemia major birth (baby with thalassaemia) would happen.

What is the best treatment for thalassemia?

Standard TreatmentsBlood Transfusions. Transfusions of red blood cells are the main treatment for people who have moderate or severe thalassemias. … Iron Chelation Therapy. The hemoglobin in red blood cells is an iron-rich protein. … Folic Acid Supplements. … Blood and Marrow Stem Cell Transplant. … Possible Future Treatments.

Does thalassemia affect immune system?

Because of this, people with thalassemia are said to be “immunocompromised,” which means that some of the body’s defenses against infection aren’t working. When you are immunocompromised, it is easier for you to get infections and you sometimes need extra protection, like flu shots and other vaccines.

Is thalassemia more common in males or females?

You are at risk for thalassemia if you have a family history of it. Thalassemia can affect both men and women. Certain ethnic groups are at greater risk: Alpha thalassemia most often affects people who are of Southeast Asian, Indian, Chinese, or Filipino descent.

Does thalassemia make you tired?

When there are not enough healthy red blood cells, there is also not enough oxygen delivered to all the other cells of the body, which may cause a person to feel tired, weak or short of breath. This is a condition called anemia. People with thalassemia may have mild or severe anemia.

Can you donate blood if you have thalassemia?

Usually, individuals with hemoglobin levels that are too low are temporarily not permitted to donate blood. A low hematocrit level is one of the most common reason people are temporarily disqualified or “deferred” from donating blood, but some donors can actually have anemia and still be eligible to donate.

Is beta thalassemia a disability?

Only those with fairly low income and assets are eligible for SSI, even if they meet the medical eligibility criteria. With regard to medical eligibility, the SSA considers beta thalassemia an inherently disabling disease.

What should we eat in thalassemia?

Nutrition & Thalassemia Nutritional deficiencies are common in thalassemia. It is recommended that patients going through blood transfusion should opt for a low iron diet. Avoiding iron-fortified foods like cereal, red meat, green leafy vegetables & Vitamin C-rich foods is the best option for thalassemic patients.

What is major thalassemia?

Thalassemia major is the most severe form of beta thalassemia. It develops when beta globin genes are missing. The symptoms of thalassemia major generally appear before a child’s second birthday. The severe anemia related to this condition can be life-threatening.

Is milk good for thalassemia?

Calcium. Many factors in thalassaemia promote calcium depletion. A diet containing adequate calcium (e.g. milk, cheese, dairy products and kale) is always recommended.

What is the treatment for beta thalassemia?

Treatment may include: Regular blood transfusions. Medicines to reduce extra iron from your body (called iron chelation therapy) Surgery to remove the spleen, if needed.

Is beta thalassemia rare?

Beta thalassemia is relatively rare in the United States, but is one of the most common autosomal recessive disorders in the world. The incidence of symptomatic cases is estimated to be approximately 1 in 100,000 individuals in the general population.

Can thalassemia be cured?

Blood transfusions and chelation do not cure beta thalassemia. A stem cell transplant can cure it, but it is a serious procedure with many risks and won’t benefit everyone with the condition. Doctors and scientist are working on developing gene therapies and other treatments to help people with beta thalassemia.

Can you have a baby if you have thalassemia?

Thalassemia in pregnancy Women with thalassemia who require blood transfusions often have a higher rate of infertility. However, some women with the disease are able to become pregnant.

How is thalassemia detected?

Doctors diagnose thalassemias using blood tests, including a complete blood count (CBC) and special hemoglobin tests. A CBC measures the amount of hemoglobin and the different kinds of blood cells, such as red blood cells, in a sample of blood.